Our team

The UKMH Investigation Unit is run by clinical experts in anaesthesia, genetics, biochemistry as well as medical researchers, technicians and administrators. Each team member plays a vital role in understanding, managing and treating MH.

MH Consultants

The role of MH consultants

1. To provide advice to patients and doctors about all clinical aspects of MH.
2. To assess referral information from anaesthetists and other clinicians to determine patient investigations for MH.
3. To provide the MH muscle biopsy service and work with genetic colleagues to provide DNA diagnostic services.

Professor Phil Hopkins

Professor Phil Hopkins

Phil is Director of the UKMH Registry, renowned globally for his research into MH. Read about Phil.

Dr Pawan Gupta

Dr Pawan Gupta

Pawan is a consultant anaesthetist.

Dr Jonathan Bilmen

Dr Jonathan Bilmen

Jonathan is an anaesthetic consultant who undertook a PhD in biochemistry and is currently researching the functional relevance of genetic discoveries.

Dr Liz Watkins

Dr Liz Watkins

Liz is a consultant anaesthetist.

Administration

Helen Binns

Helen Binns

Helen is responsible for administration at the MH unit and is the first point of contact for patients and clinicians. 

Diagnostic Team

Dr Dorota Miller

Dr Dorota Miller

Dorota is a senior clinical scientist and research fellow. She conducts in vitro contracture tests and leads genetic discovery research and findings into diagnostic use.

Helena Wright

Helena Wright

Helena is a senior laboratory technician who carries out quality control procedures for the European MH group.

Catherine Daly

Catherine Daly

Catherine is a senior laboratory technician who conducts contracture tests, supervises the technical team and manages the research database.

Sarah Hobson

Sarah Hobson

Sarah is a laboratory technician who undertakes contracture tests and genetic screening, including Next Generation Sequencing.

Research Staff

Dr Marie-Anne Shaw

Dr Marie-Anne Shaw

Marie-Anne is an Associate Professor in human genetics who has carried out specialist research into the genetics of MH for over 20 years.

Kiran Riasat

Kiran Riasat

Kiran is a laboratory technician who assists in all areas of research and is funded by a National Institute of Health grant.

Research Students

Lois Gardner

Lois Gardner

Lois is a PhD student who is currently researching exertional heat illness and its relationship to MH.

James Lowe

James Lowe

James is currently researching micro RNA binding sites found within genes associated with MH, as well as testing the difference in microRNA expression between susceptible and normal patients

Leon Chang

Leon Chang

Leon is investigating evidence of differential gene expression in MH muscle biopsies, taken for diagnostic contracture testing, before and after exposure to caffeine and halothane. Employing bioinformatics approaches, expression quantitative trait loci (eQTLs) will be identified. Such eQTLs provide candidate loci for the control of MH and related phenotypes, which will be tested and analysed by genetic association methods.

Katie Nicholl Baines

Katie Nicholl Baines

Katie is a PhD student and demonstrator in anatomy on the MB ChB medical student degree programme. Katie’s PhD project focuses on the impact on ageing of variants in the RYR1 gene.

Rachel Dodds

Rachel Dodds

Rachel is a PhD student investigating the molecular mechanisms of calcium dysregulation in MH susceptibility.  Using the ground-breaking gene-editing technique, CRISPR-Cas9, the functional relevance of genetic variants identified in MH susceptible individuals will be determined.  This research will speed up the identification of variants that cause MH and broaden the availability of DNA diagnostics.

Vikas Kaura

Vikas Kaura

Vikas is undertaking an MRC funded Clinical Research Training Fellowship investigating the molecular mechanisms involved in MH. His project stems from our knowledge that patients who are at risk of MH have changes in some of the proteins within their cells that then affects the way calcium enters, moves around and leaves their muscle cells. The results of his research will allow us to understand exactly how these genetic changes affect the different proteins involved in regulating the levels of calcium within the cell. This will further increase our knowledge of the disease as well as related conditions, and could allow for improvements in the diagnosis and treatment of MH.